Global transient amnesia5/15/2023 He seemed stunned to find out he no longer lived there. When asked his name and address, he responded promptly, but the address he gave was the house he shared for many years with his future ex-wife. Except he couldn’t remember the events of the recent past. He had a scrape on his right cheek and over his eye, but otherwise he seemed fine. No one could tell her any more than that, and her father clearly didn’t remember. His soon-to-be ex-wife was also in the E.R., and again and again he asked her: Are we really getting divorced? Why? What happened?Įarlier that day, his daughter received a call from the hospital saying that her father had fallen outside the supermarket and was brought in by an ambulance called by a good Samaritan. He didn’t even remember that he had spent the past few months hashing out a pretty messy divorce. Didn’t remember that he spent the morning moving the last of the boxes he had stored at his daughter’s house to his new apartment. The man nodded, as if taking it all in, but minutes later asked again: Where am I? He had never had any memory issues before, but now he couldn’t remember that it was Saturday. He had been found on the ground in the parking lot of the grocery store near his apartment. His daughter explained again: He was at Yale-New Haven Hospital in Connecticut. Submitted comments are subject to editing and editor review prior to posting.“Where am I?” the 68-year-old man asked.Read any comments already posted on the article prior to submission. Submit only on articles published within 6 months of issue date.(Exception: original author replies can include all original authors of the article) Submissions should not have more than 5 authors.Reference 1 must be the article on which you are commenting. Submissions must be You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid If you are responding to a comment that was written about an article you originally authored: Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment. You must have updated your disclosures within six months: If you are uploading a letter concerning an article: 5,6 ⇓Ĭan MRI help provide answers? The profound nature of the memory deficit has encouraged speculation that … View Full Text The same group has reported that a significantly higher percentage of TGA patients possess jugular venous backflow with Valsalva compared with controls. 4 Interestingly, there is some support for this hypothesis. More recently, Lewis hypothesized that TGA was related to venous congestion due to retrograde venous cerebral blood flow, because of the commonly reported association between TGA and situations that result in reduced venous return and retrograde venous blood flow (e.g., sexual activity, stress, Valsalva maneuver). 3 Unfortunately, definitive evidence supporting any of these mechanisms has been lacking. 3 Even a neuropsychological cause has been proposed. Various proponents have advocated ischemic, migrainous, and epileptic causes. What causes TGA? For years this question has been debated. There are no apparent long-term sequelae, and recurrence is uncommon. 1,2 ⇓ As quickly as the amnesic syndrome appears, it resolves, usually within 24 hours. Without warning, the patient suddenly experiences antegrade memory loss. Transient global amnesia (TGA) is a dramatic event.
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